Hello people, I'm back.
My husband and I finally feel ready to under go our 2nd round of ICSI fertility treatement and we have an appointment on the 19th July to see our consultant to get the ball rolling, so keep your fingers and toes crossed for us this time.
Sunday, 26 June 2011
Sunday, 20 February 2011
Decided to delay 2nd cycle of fertility treatment
After a lot of discussion we decided we are not ready to under go our 2nd round of fertility treatment just yet, but will continue in a few months!!!
Friday, 10 September 2010
The 2nd Cycle Begins
Dave and I have an appointment booked for the 13th of December to talk to a consultant about starting our 2nd ICSI cycle the following month, so thats all until then ................................
What we have Decided to do now
Hello people, After taking some time out to come to terms with our negative result Dave and I have decided to have another cycle of ICSI at the Peninsular Centre for Reproductive Medicine in Exeter starting this coming January (2011).
This time will be paid for by ourselves as the NHS will only fund one cycle of ICSI in our area.
So now its time to knuckle down and save hard for the next few months.
This time will be paid for by ourselves as the NHS will only fund one cycle of ICSI in our area.
So now its time to knuckle down and save hard for the next few months.
The debrief Appointment for our failed cycle of ICSI (4th August 2010)
Today we wen to our debrief appointment for our failed cycle of ICSI, our appointment was with the nurse Manager at the Peninsular Centre for Reproductive Medinicne, Exeter.
The discussion centered around what had been learned from this 1st cycle that may apply to any further treatments we may under go in the future for example it seems there may have been a slight intolerance to the injecting procedure with my eggs resulting in a low usable yield. This may have of course just been coincidental but it was worth noting.
Dave and I also learnt that the two embryos transfered were both grade two embryos and both were four cells.
We went on to discuss what our options were now and then sent home to talk about everything and decide together what we wanted to do and when.
The discussion centered around what had been learned from this 1st cycle that may apply to any further treatments we may under go in the future for example it seems there may have been a slight intolerance to the injecting procedure with my eggs resulting in a low usable yield. This may have of course just been coincidental but it was worth noting.
Dave and I also learnt that the two embryos transfered were both grade two embryos and both were four cells.
We went on to discuss what our options were now and then sent home to talk about everything and decide together what we wanted to do and when.
Saturday, 3 July 2010
2nd Test Day to confirm Result 02/07/2010
as mentioned in mu last post we have faced our worst fear, a negative pregnancy test result, but now have to test again for absolute confirmation.
So at 6am on 02/07/2010 I repeated the pregnancy test, It is strange doing a test under these circumstances and what comes to mind is how different it feels compared with how it must feel for a normal fertile couple doing the same test, The potential joy is offset by the dread of what is almost certainly going to be a negative result.
5minutes passes and pretty much as expected we observe another negative result, this being the final conformation that I am not pregnant.
At this stage it is agreed that you have to make contact with the fertility clinic so they are fully up to date with the situation, so having left a message on there answer phone I received a phone call back from them and gave them the bad news. During this phone call I was instructed to stop taking the fertility medications, I also asked how I should proceed with regards to starting another treatment cycle and what options may be available to me now.
So at 6am on 02/07/2010 I repeated the pregnancy test, It is strange doing a test under these circumstances and what comes to mind is how different it feels compared with how it must feel for a normal fertile couple doing the same test, The potential joy is offset by the dread of what is almost certainly going to be a negative result.
5minutes passes and pretty much as expected we observe another negative result, this being the final conformation that I am not pregnant.
At this stage it is agreed that you have to make contact with the fertility clinic so they are fully up to date with the situation, so having left a message on there answer phone I received a phone call back from them and gave them the bad news. During this phone call I was instructed to stop taking the fertility medications, I also asked how I should proceed with regards to starting another treatment cycle and what options may be available to me now.
The End Of The 2 Week Wait - Test Day 30/06/2010
Today is the day we have been waiting for, for 2 weeks. We both were excited but felt sick with nerves as well.
I woke up at 4:20am and went straight to the bathroom to do the pregnancy test, I brought the test stick back into our bedroom to sit with Dave to wait for the results (I did 2 pregnancy tests just in case).
Our worst fears had become reality, a clear negative result was observed on both test sticks and at this moment we both knew that this roller coaster of emotions was far from over, We had to face some choices as to what to do next.
Although the results were clear enough we still had to test again 2 days later to give a 100% verdict just in case any of the timings were slightly mis calculated.
I woke up at 4:20am and went straight to the bathroom to do the pregnancy test, I brought the test stick back into our bedroom to sit with Dave to wait for the results (I did 2 pregnancy tests just in case).
Our worst fears had become reality, a clear negative result was observed on both test sticks and at this moment we both knew that this roller coaster of emotions was far from over, We had to face some choices as to what to do next.
Although the results were clear enough we still had to test again 2 days later to give a 100% verdict just in case any of the timings were slightly mis calculated.
Wednesday, 16 June 2010
The Embryo Transfer (implantation) 16th June 2010
This morning at approximatively 10:14 we received a phone call from Jo the embryologist at the Peninsular Centre for Reproduction Medicine to say its all systems go and our embryos are cell diving as they should.
Later on we attending our appointment to have the embryos implanted and at precisely 4 o clock the procedure was completed.
This procedure is done drug free, using a ultrasound machine and a catheter.
All that is left to do now is to keep taking the Antibiotic Cepfradine until friday, also to keep taking Progynova and Cyclogest Twice a day and do a pregnancy test in 2 weeks time.
Later on we attending our appointment to have the embryos implanted and at precisely 4 o clock the procedure was completed.
This procedure is done drug free, using a ultrasound machine and a catheter.
All that is left to do now is to keep taking the Antibiotic Cepfradine until friday, also to keep taking Progynova and Cyclogest Twice a day and do a pregnancy test in 2 weeks time.
Tuesday, 15 June 2010
Tuesday 15th June 2010
Today I received a phone call from the embryologist at The Peninsular Centre for Reproductive Medicine.
From the 8 Eggs that were collected in my Egg retrieval yesterday only 5 Eggs were mature enough for treatment.
From the 5 mature Eggs remaining 3 eggs were not viable to be injected with sperm so they died.
This leaves us with 2 fertilized strong and healthy embryos.
An appointment has been scheduled for 3pm tomorrow afternoon to implant the 2 strong and healthy embryos.
Although we had no embryos to freeze in this cycle it is still very much a positive outcome so far.
From the 8 Eggs that were collected in my Egg retrieval yesterday only 5 Eggs were mature enough for treatment.
From the 5 mature Eggs remaining 3 eggs were not viable to be injected with sperm so they died.
This leaves us with 2 fertilized strong and healthy embryos.
An appointment has been scheduled for 3pm tomorrow afternoon to implant the 2 strong and healthy embryos.
Although we had no embryos to freeze in this cycle it is still very much a positive outcome so far.
Final drugs part 2 (15th June 2010)
Along side Cyclogest I started taking Progynova 2mg Tablet (Estradiol Valerate).
This works along side the Cyclogest to maintain endometrium. The combination of these drugs along with a little luck will help a pregnancy until the body resumes the production of normal hormones.
Progynova should also be taken twice a day (12 hours apart) until I am 12 weeks pregnant, unless the pregnancy is unsuccessful.
This works along side the Cyclogest to maintain endometrium. The combination of these drugs along with a little luck will help a pregnancy until the body resumes the production of normal hormones.
Progynova should also be taken twice a day (12 hours apart) until I am 12 weeks pregnant, unless the pregnancy is unsuccessful.
The Final Drugs (14th June 2010)
The evening after my Egg retrieval I started Taking Cyclogest 400mg Pessaries (Progesterone PhEur).
Progesterone is a hormone produced by the ovary that sustains an early pregnancy.
This hormone is also responsible for premenstrual sysptoms such as bloating, breast tenderness or feeling that your period is imminent.
I to take Cyclogest twice a day (12 hours apart) until I am 12 weeks pregnant unless the pregnancy is unsuccessful.
Progesterone is a hormone produced by the ovary that sustains an early pregnancy.
This hormone is also responsible for premenstrual sysptoms such as bloating, breast tenderness or feeling that your period is imminent.
I to take Cyclogest twice a day (12 hours apart) until I am 12 weeks pregnant unless the pregnancy is unsuccessful.
Monday, 14 June 2010
The Egg Collection and TESA Procedure (14th June 2010)
Today I had my Egg retrieval and Dave had his TESA procedure (Sperm Collection).
We got to the Peninsular Centre for Reproductive Medicine for 8am, There was a little wait while the last of the paperwork was done then at about 09:40am I Was called in to the theater (Dave was allowed to come in with me).
A sedative was injected in to my hand by a cannula and with in 5 mins the procedure was under way.
Using a probe to aspirate the follicles the surgeon quickly aspirated fluid from the follicles containing the eggs, in total the surgeon harvested 8 eggs, This was all visible on the monitor though difficult to watch while sedated.
The whole procedure only took about 20-25 mins then I was wheeled back to the ward, where I was put on a blood pressure machine and monitored.
Dave went to theater at about 10:05am, almost immediately after entering the theater the procedure began with several local anesthetic injections. Then the process of aspiration begins, this involves extracting tubules from the testicle one at a time, till approximatively 8 samples have been harvested. This procedure also only took 20-25mins.
We got to the Peninsular Centre for Reproductive Medicine for 8am, There was a little wait while the last of the paperwork was done then at about 09:40am I Was called in to the theater (Dave was allowed to come in with me).
A sedative was injected in to my hand by a cannula and with in 5 mins the procedure was under way.
Using a probe to aspirate the follicles the surgeon quickly aspirated fluid from the follicles containing the eggs, in total the surgeon harvested 8 eggs, This was all visible on the monitor though difficult to watch while sedated.
The whole procedure only took about 20-25 mins then I was wheeled back to the ward, where I was put on a blood pressure machine and monitored.
Saturday, 12 June 2010
The Final Injection (12th June 2010)
Yippee With the final injection done (pregnyl) I now just wait until our appointment in 36hours time at the Peninsular Centre for Reproductive Medicine where the egg retrieval and Dave's TESA procedure will take place.
The Last of my Buserelin and Puregon Drugs (12th June 2010)
Today at 6am I injected my Buserelin and Puregon drugs for the very last time, YIPPEE!!!!
I also took the last of my steroid tablets, but I had to start my course antibiotic tablets.
I took two different Antibiotics they are Called Cephradine (250mg 3 times a day for 7 days) and Doxycycline (100mg twice a day for 2 days).
Tonight at 10PM I will inject my last ever injection, which is Pregnyl (HCG)
Pregnyl injections are used to stimulate follicules to mature and ovulation to occur, it comes in a box with 2 glass containers, one is a liquid the other is a powder, these need to be mixed together and injected at the exact time your fertility nurse tells you to (normally 35 - 36 hours before Egg collection).
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I also took the last of my steroid tablets, but I had to start my course antibiotic tablets.
I took two different Antibiotics they are Called Cephradine (250mg 3 times a day for 7 days) and Doxycycline (100mg twice a day for 2 days).
Tonight at 10PM I will inject my last ever injection, which is Pregnyl (HCG)
Pregnyl injections are used to stimulate follicules to mature and ovulation to occur, it comes in a box with 2 glass containers, one is a liquid the other is a powder, these need to be mixed together and injected at the exact time your fertility nurse tells you to (normally 35 - 36 hours before Egg collection).
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Friday, 11 June 2010
The Finale Scan 11th June 2010
Today I had my final scan before the procedure to remove my eggs at Peninsular Centre for Reproductive Medicine.
I have responded as expected to the fertility drugs and the results suggest
I have 8 follicles in my right ovary and 5 follicles in my left ovary, but 3 are a little small, which leaves 10 good size follicles to use in my egg collection on Monday.
Then after the scan the fertility nurse showed me how to mix up the pregnyl which is the last drug that I will be injecting on this cycle.
I have responded as expected to the fertility drugs and the results suggest
I have 8 follicles in my right ovary and 5 follicles in my left ovary, but 3 are a little small, which leaves 10 good size follicles to use in my egg collection on Monday.
Wednesday, 2 June 2010
Today I started injecting another medication called Puregon, this is as well as still injecting Buserelin, so now I am on two injections every morning and also I now have to take a steroid tablets called Betamethasone.
There are multiple reasons for these other medications being taken now which are firstly to improve FSH response and to aid implantation but also there is evidence of a lower miscarriage rate if taking a steroid of this nature.
Tuesday, 1 June 2010
The 1st Scan Tuesday 1st June 2010
Today I had my first scan to see if the Buserelin drug has been doing its job (preventing ovulation).
This scan is a vaginal scan, its done by what I call the dildo cam!!
I also had to have vaginal swobs to test for any STI's to update my file.
Tomorrow I will start injecting my 2nd fertility drug and start my steroid tablets, whilst still injecting Buserelin
Tuesday, 25 May 2010
Pre-Op Assessment (25th May 2010)
Today we had our our pre-op Assessment with Sister Denise Davies at the Peninsular Centre for Reproductive Medicine.
Both Dave and I were weighed and had our blood pressure checked, then we sat down and answered questions relating to our general health and well being.
The sister described in more detail the process involved in doing the retrieval of the eggs and sperm, now as we get closer to that day a small amount of fear is creeping in!!!
All in all the Sister did her best to reassure us both about the retrieval process and I think she has to paint a picture on the more severe side so there are no nasty surprises on the day.
Both Dave and I were weighed and had our blood pressure checked, then we sat down and answered questions relating to our general health and well being.
The sister described in more detail the process involved in doing the retrieval of the eggs and sperm, now as we get closer to that day a small amount of fear is creeping in!!!
All in all the Sister did her best to reassure us both about the retrieval process and I think she has to paint a picture on the more severe side so there are no nasty surprises on the day.
Tuesday, 18 May 2010
The 1st Buserelin Injection (18th May 2010)
This morning started like any other morning except that on this morning at 6am I would have to over come one of my greatest fear, the fear of needles.
Too nervous to administer it myself Dave did it for me and with in less then a minute and one short sharp sting in the thigh it was all over, now it remains to be seen weather it gets easier each day as we go on!
The drug we injected today was called Buserelin, the amount to be injected daily is 0.3ml.
The drug also has to be injected at the same time every day, (we have chosen 6am).
Too nervous to administer it myself Dave did it for me and with in less then a minute and one short sharp sting in the thigh it was all over, now it remains to be seen weather it gets easier each day as we go on!
The drug we injected today was called Buserelin, the amount to be injected daily is 0.3ml.
The drug also has to be injected at the same time every day, (we have chosen 6am).
The Last Contraception pill (17th May 2010)
Today I took the last ever of the contraception pill...... yippee!!!
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